| | Date | Opponent | | Score | | | Overall | Conference | Attend | Goals scored |
| | Sep 03, 2010 | NORTHEASTERN | W | 2-1 | | O2 | 1-0-0 | 0-0-0 | 1077 | Colchao, Jose (Christianson, Ian;DILLON, Joey) |
| | | | | | | | | | | Onyeador, Uche (Neumann, Steve) |
| | Sep 05, 2010 | #24 MICHIGAN STATE | W | 4-0 | | | 2-0-0 | 0-0-0 | 1017 | Onyeador, Uche (Nealis, Jimmy) |
| | | | | | | | | | | Riemer, Andy (unassisted) |
| | | | | | | | | | | Neumann, Steve (Dillon, Joey;C'DEBACA, Seth) |
| | | | | | | | | | | Padilla, Gabe (Riemer, Andy;NEUMANN, Steve) |
| | Sep 10, 2010 | at New Mexico | | 1-3 | L | | 2-1-0 | 0-0-0 | 4430 | Verdi, Alex (unassisted) |
| | Sep 12, 2010 | at Denver | | 1-3 | L | | 2-2-0 | 0-0-0 | | Christianson, Ian (penalty kick) |
| | Sep 17, 2010 | at Princeton | | 1-1 | T | O2 | 2-2-1 | 0-0-0 | 918 | C'deBaca, Seth (Diggs, Chandler) |
| | Sep 19, 2010 | #22 PENNSYLVANIA | | 1-3 | L | | 2-3-1 | 0-0-0 | 771 | Muller, Tommy (C'deBaca, Seth) |
| * | Sep 25, 2010 | at Cincinnati | | 0-2 | L | | 2-4-1 | 0-1-0 | 178 | - |
| | Sep 29, 2010 | ADELPHI | W | 2-0 | | | 3-4-1 | 0-1-0 | 221 | Dillon, Joey (Neumann, Steve;CHRISTIANSON, Ian) |
| | | | | | | | | | | Muller, Tommy (Neumann, Steve) |
| * | Oct 02, 2010 | #21 WEST VIRGINIA | W | 1-0 | | | 4-4-1 | 1-1-0 | 743 | Christianson, Ian (penalty kick) |
| | Oct 06, 2010 | at AMERICAN | W | 3-2 | | | 5-4-1 | 1-1-0 | 168 | Colchao, Jose (C'deBaca, Seth) |
| | | | | | | | | | | Neumann, Steve (Christianson, Ian;PADILLA, Gabe) |
| | | | | | | | | | | Neumann, Steve (Riemer, Andy) |
| * | Oct 09, 2010 | at Providence College | W | 1-0 | | | 6-4-1 | 2-1-0 | 417 | Neumann, Steve (Tembon, Henry;NEALIS, Jimmy) |
| * | Oct 13, 2010 | SETON HALL | W | 6-0 | | | 7-4-1 | 3-1-0 | 107 | Muller, Tommy (Neumann, Steve) |
| | | | | | | | | | | Diggs, Chandler (unassisted) |
| | | | | | | | | | | Neumann, Steve (BURNETT, Rob;C'DEBACA, Seth) |
| | | | | | | | | | | Neumann, Steve (Tembon, Henry;C'DEBACA, Seth) |
| | | | | | | | | | | Colchao, Jose (Christianson, Ian) |
| | | | | | | | | | | Padilla, Gabe (Otegbeye, Ibu;DILLON, Joey) |
| * | Oct 16, 2010 | VILLANOVA | W | 3-1 | | | 8-4-1 | 4-1-0 | 1035 | Neumann, Steve (Diggs, Chandler;COLCHAO, Jose) |
| | | | | | | | | | | Neumann, Steve (Colchao, Jose;CHRISTIANSON, Ian) |
| | | | | | | | | | | Colchao, Jose (Neumann, Steve) |
| * | Oct 20, 2010 | at Pittsburgh | W | 1-0 | | | 9-4-1 | 5-1-0 | 136 | Colchao, Jose (C'deBaca, Seth) |
| * | Oct 23, 2010 | MARQUETTE | W | 6-2 | | | 10-4-1 | 6-1-0 | 1279 | Riemer, Andy (C'deBaca, Seth;NEALIS, Jimmy) |
| | | | | | | | | | | Christianson, Ian (Diggs, Chandler;NEUMANN, Steve) |
| | | | | | | | | | | Christianson, Ian (BURNETT, Rob;C'DEBACA, Seth) |
| | | | | | | | | | | Neumann, Steve (Tembon, Henry;COLCHAO, Jose) |
| | | | | | | | | | | Diggs, Chandler (Christianson, Ian;COLCHAO, Jose) |
| | | | | | | | | | | Diggs, Chandler (Nealis, Jimmy;MULLER, Tommy) |
| * | Oct 28, 2010 | #6 CONNECTICUT | W | 1-0 | | | 11-4-1 | 7-1-0 | 1089 | Neumann, Steve (Christianson, Ian) |
| * | Oct 31, 2010 | at Notre Dame | | 0-3 | L | | 11-5-1 | 7-2-0 | 327 | - |
| | Nov 06, 2010 | PROVIDENCE COLLEGE | | 1-2 | L | | 11-6-1 | 7-2-0 | 937 | Slingerland, Ben (Neumann, Steve) |
| | Nov 18, 2010 | UNC GREENSBORO | W | 3-0 | | | 12-6-1 | 7-2-0 | 385 | Christianson, Ian (Colchao, Jose) |
| | | | | | | | | | | Riemer, Andy (C'deBaca, Seth) |
| | | | | | | | | | | Diggs, Chandler (Colchao, Jose) |
| | Nov 21, 2010 | at #4 North Carolina | | 0-0 | T | O2 | 12-6-2 | 7-2-0 | 651 | - |
